PUK and systemic autoimmune disease
Corneal diagnoses and systemic disease PUK and systemic autoimmune disease by Michelle Dalton EyeWorld Contributing Editor PUK is clearly identifiable in this patient Source: Sophie X. Deng, M.D. An example of marginal (limbal) herpes simplex keratitis (mimicking PUK) Source: Vincent P. de Luise, M.D. Mooren's ulcer caused this patient's PUK Source: Vincent P. de Luise, M.D. Usually considered an ocular manifestation of a systemic autoimmune disorder, peripheral ulcerative keratitis can result in devastating outcomes—including permanent loss of vision Peripheral ulcerative keratitis (PUK) is typically associated with poorly managed systemic conditions such as rheumatoid arthritis (RA accounts for almost one-third of non-infectious PUK), among others. What can cause it? "VAST CRIMES," said Vincent P. de Luise, M.D., assistant clinical professor of ophthalmology, Yale University School of Medicine, New Haven, Conn. PUK can be caused by ...